
Myostatin Blockers Cut GLP-1 Muscle Loss. Strength Is Unproven
Trevogrumab and apitegromab saved kilograms of lean tissue in phase 2 trials, but no study has yet shown that it makes anyone stronger.
Topic
Muscle mass, strength and body composition: what training and drugs actually change, and how the change was measured.

Trevogrumab and apitegromab saved kilograms of lean tissue in phase 2 trials, but no study has yet shown that it makes anyone stronger.
Twelve weeks of lifting: vegetarians gained 0.38 kg of limb muscle, omnivores 0.66 kg. The trial could not show the two diets were equivalent.

Sironax's FORGE-LM trial is half enrolled. The endpoint is body composition, which is the right question. Enrollment, though, is not a result.
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